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br Transparency document br Acknowledgements This work was
2019-07-30
Transparency document Acknowledgements This work was supported by research grant G092715N of the Research Foundation Flanders (FWO). The authors are indebted to Drs. V. Baekelandt and E. Lobbestael (Research Group for Neurobiology and Gene Therapy, KU Leuven) for stimulating discussions and he
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Atipamezole hydrochloride Fig S an adrenoceptor antagonist i
2019-07-30
Atipamezole hydrochloride (Fig. S1), an α2-adrenoceptor antagonist, is commonly used by veterinarians to recover animals from sedation-anesthesia induced by α2-adrenoceptor agonists. Recent studies in animals suggest that atipamezole might have beneficial effects in Pergolide mesylate damage repair,
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In our model CSF R
2019-07-30
In our model, CSF-1R blockade with PLX647 mainly targeted the more abundant MDSCs instead of macrophages, suggesting that the role of CSF-1 may be tumor model-dependent. Different tumor models, genetic backgrounds, or treatments may induce different growth factors or cytokines in the tumor microenvi
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br Introduction Abdominal aortic aneurysm AAA is a
2019-07-29
Introduction Abdominal aortic aneurysm (AAA) is a daily concern in vascular surgery, as successful treatment is exclusively achieved by open or endovascular repair. Its prevalence is 2–11% among male smokers, and rupture the major complication, is associated with unacceptably high morbidity and m
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CFDA-SE br Genes involved in oxysterol metabolism The main
2019-07-29
Genes involved in oxysterol metabolism The main enzymes that participate in the metabolism of oxysterols generally belong into one of two groups: transferases or oxidoreductases [22]. The following chapter describes those genes of oxysterol metabolism whose polymorphisms have been associated with
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The folate pathway plays an essential role in cell
2019-07-29
The folate pathway plays an essential role in cell survival by generating 5, 10-methylene tetrahydrofolate as a one-carbon donor for the synthesis of deoxythymidine monophosphate (dTMP), purines, methionine and histidine. Disruption of this pathway leads to the critical deficiency of these key molec
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Recent studies have shown arsenic could cause autophagic cel
2019-07-29
Recent studies have shown arsenic could cause autophagic cell death in malignant cells, including leukemia and malignant glioma sphingosine-1-phosphate [16], [17]. However, at present, little is known about the consequences of arsenic-treated urothelial cells in autophagy and expression of its rela
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br Materials and methods br Results br
2019-07-29
Materials and methods Results Discussion CHIKV is an important arthropod borne virus with substantial impact on global health and cause a major viral disease that requires the development of antiviral drug to combat chikungunya disease. Virus specific proteases have particularly become an a
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HEK cells stably transfected with CysLT were stimulated with
2019-07-29
HEK-293 KP372-1 where stably transfected with CysLT1 were stimulated with LTD and internalization was studied by confocal microscopy, FACS or cell-surface ELISA. Cells were co-transfected with wildtype and dominant negative (DN) mutants of arrestin and dynamin. Clathrin-mediated endocytosis was in
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Results from H also complement work
2019-07-29
Results from H5 also complement work of the AICPA Board of Examiners, which has concluded “newly licensed CPAs must demonstrate higher-order skills such as critical thinking, problem solving, analytical ability, and skepticism more frequently. It is critically important that newly licensed CPAs are
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Esomeprazole Sodium to CPH models reported usually as lists
2019-07-29
CPH models, reported usually as lists of risk factors along with their parameters, are prevalent in medical literature. One such model is the CPH model created for the purpose of predicting the probability of one year survival of patients suffering from Pulmonary Arterial Hypertension [5]. The model
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br Results with scrubbing process Based on the
2019-07-29
Results with scrubbing process Based on NAD/NADH Quantitation Colorimetric Kit to discussion of Section 4.4 and area availability results of the previous section, scrubbing process, at the pixel processing rate, was included to mitigate error accumulation on the arrays and on the line-buffer. Ei
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chemokine receptor A comparison between tinnitus and
2019-07-29
A comparison between tinnitus and controls subjects showed increased activity in the left AUD and PHC for the gamma frequency band. The link between gamma band activity in the AUD and tinnitus has been identified using both EEG (van der Loo et al., 2009) and MEG (Weisz et al., 2005, 2007). This is s
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This study has several limitations First despite the relativ
2019-07-29
This study has several limitations. First, despite the relatively large number of participants for a pharmacological neuroimaging study, sample sizes for examining the modulation of THC effects by COMT AMD3100 8HCl were small. Therefore, these particular findings should be interpreted with caution
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The modes of action of insecticides are classified by
2019-07-29
The modes of action of insecticides are classified by the Insecticide Resistance Action Committee (IRAC) [6]. In this classification, a large proportion of insecticides are categorized as nerve- and muscle-targeting insecticides, which encompass GABACl antagonists (Group 2) and GluCl allosteric modu
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