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Data from related literature has suggested that arthrocentes
2018-11-03
Data from related literature has suggested that arthrocentesis may be of some benefit to manage symptoms of TMDs. Such a technique was first introduced for the management of sudden onset of closed lock [3]. Arthrocentesis is the single most important non-invasive procedure in musculoskeletal medicin
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br Part The Egyptian Education System
2018-11-03
Part 2: The Egyptian Education System: a focus on a single learning mode Part 3: Relevant findings linked to the use of CBS in an Egyptian cultural context, in an Egyptian-French dual degree programme Conclusion: what did we learn? As shown in some of the notes, the reactions of the student
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br Introduction The rate of
2018-11-03
Introduction The rate of hepatitis B infection is very high in China, and hepatitis B can chronically induce cirrhosis and primary hepatocellular carcinoma. Hepatitis B has become a social problem compromising the health of civilians in China, and Chinese patients comprise about one third of all
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br Introduction Mesenchymal stem cells MSCs have been thorou
2018-11-02
Introduction Mesenchymal stem WP1130 cost (MSCs) have been thoroughly studied during the past two decades. MSCs are multipotent cells that can replicate and have the potential to differentiate into lineages of mesenchymal tissues, including bone, cartilage, and fat. They are also characterized b
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br Polyphenols tea polyphenols red wine
2018-11-02
Polyphenols (tea polyphenols, red wine polyphenols and chocolate polyphenols) Polyphenols are natural organic compounds rich in fruits and vegetables, tea, red wine, honey and cocoa beans. Polyphenols with multiple hydroxyl groups can effectively remove free radicals including O2− and singlet oxy
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As the stem cells were recovered from bears
2018-11-02
As the stem HZ-1157 were recovered from bears that recently were hibernating, it is possible that circulating factors that protect the bear from bone degeneration during hibernation prime the stem cells. That we did not see any chondrogenic differentiation in the cultures exposed to the chondrogeni
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An interesting remaining question is
2018-11-02
An interesting remaining question is whether hemogenic endothelial cells are already committed to producing blood or whether any endothelial cell is capable of doing so depending on the influence of a singular environment. It is of interest to note that hemogenic endothelial cells found in different
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In our model DNA damage forces cells
2018-11-02
In our model, DNA damage forces cells into cellular senescence, whereas ATM-dependent and p53-antagonized cytokine secretion activates BMP2/JAK-STAT signaling and stimulates the differentiation process in a progressive feed-forward manner. This senescent state is very different from the GFAP-associa
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A whole genome transcriptome analysis was carried out to
2018-11-02
A whole genome transcriptome analysis was carried out to clarify the mechanisms of the cell type specific cytotoxicity of HDAC inhibition on the abnormal cells. The transcriptome analysis revealed the HDAC inhibitor responsive genes in the normal and abnormal cells. The genes with altered levels in
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Safe Ca antagonists are already used clinically and convinci
2018-11-02
Safe Ca2+ antagonists are already used clinically, and convincing (albeit limited) evidence supports their use in LQTS diseases that resist conventional pharmacotherapy (Iseri and French, 1984; Jackman et al., 1990; Komiya et al., 2004). However, physicians appear hesitant to prescribe Ca2+ antagoni
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Finally Expression of Sox alone was sufficient to induce
2018-11-02
Expression of Sox2 alone was sufficient to induce neurogenesis without requirement for coexpression of a proneural transcription factor. This is surprising, as Sox2 function in neural stem cells is to promote self-renewal rather than neuronal differentiation (Graham et al., 2003; Pevny and Nicolis,
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br Experimental Procedures br Acknowledgments We thank Ms Y
2018-11-02
Experimental Procedures Acknowledgments We thank Ms. Y. Ogata for technical assistance. Financial support for this research was provided by The Uehara Memorial Foundation, and The Ministry of Education, Culture, Sports, Science, and Technology of Japan and the Japan Science and Technology Agen
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br Results br Discussion Here we
2018-11-02
Results Discussion Here we report on 14 different mutant hESC lines, termed DM1 hESCs, that were derived from DM1-affected preimplantation embryos. Previous studies employed DM1 hESCs to explore the causal role of CTG expansion on neurite formation and neuromuscular connections and for charact
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c-kit inhibitor To determine tissue specificity in CESC
2018-11-02
To determine tissue specificity in CESC differentiation, we performed chondrogenic and osteogenic induction under normoxia and hypoxia, respectively. Our study revealed tissue specificity indicating that hypoxia promoted chondrogenesis but inhibited osteogenesis in CESCs. This tissue specificity of
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DENV as one of the most
2018-11-02
DENV, as one of the most widespread vector-borne viruses, infects millions of people each year worldwide. However, no clinically approved drugs are yet available against DENV. There is an urgent need to develop effective anti-DENV drugs for such treatment. In this study we tested IFN-α2a, chloroquin
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