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Direct competition between lysine acetylation and ubiquitina
2018-11-05
Direct urotensin ii between lysine acetylation and ubiquitination has been proposed as a major mechanism regulating protein stability and has primarily been documented in cancer progression. p53, E2F1, SKP2, and MSH2 have been reported to be regulated by lysine acetylation and ubiquitination, which
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Let us consider in detail the main results
2018-11-05
Let us consider in detail the main results of the measurements. The laser ablation threshold density in the microsecond and nanosecond ranges depending on the sample light transmittance of nanocomposites for five samples of SiO2 coatings is shown in the graphs of Fig. 4a. These dependencies were f
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br Identification of radio objects from the NVSS survey In
2018-11-05
Identification of radio objects from the NVSS survey In 1992–1998, a survey of the northern sky was carried at the National Radio Astronomy Observatory (NRAO), USA [7,12] using an interferometer, at a frequency of 1400MHz, with a directivity pattern θ=45″ and a sensitivity of 2.5mJy. The data of
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br Design and methods br Results br Discussion
2018-11-05
Design and methods Results Discussion Using O/E-based analyses, we found clustering at both ends of the risk continuum: not meeting recommendations for any behaviour and meeting all the recommendations occurred more than would be expected if the behaviours were independent. In studies of th
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br Conflict of interest br Acknowledgements The HBSC is a
2018-11-05
Conflict of interest Acknowledgements The HBSC is a WHO/Euro collaborative study; International Coordinator of the 2014 study was Candace Currie, St. Andrews University, Scotland; Data Bank Manager is Oddrun Samdal, University of Bergen, Norway. The 6 countries involved in this analysis (curre
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br Conclusion br Introduction Scholars of immigrant health h
2018-11-05
5. Conclusion Introduction Scholars of immigrant health have long focused on immigrants׳ health advantage relative to U.S.-born counterparts, despite lower average socio-economic status. The so-called “immigrant paradox” is typically linked to migrants׳ favorable health behaviors (Blue & Fenel
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br Methods br Measures br Statistical analyses
2018-11-05
Methods Measures Statistical analyses Data analysis was conducted at the [blinded] Research Data Centre using STATA statistical software (version 14) (Statacorp, College Station, TX, 2015). Marginal effect DR 4485 hydrochloride analyses were calculated to quantify the potential reduction
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RVX-208 Supplier While in developed countries a home death i
2018-11-05
While in developed countries, a home death is considered a good death, however, in sub-Saharan African countries this RVX-208 Supplier may have a different implication in that a person who dies at home could have failed to access and utilize health care services. Conversely, an individual who dies
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Satisfaction with CSR initiatives therefore becomes a key me
2018-11-05
Satisfaction with CSR initiatives therefore becomes a key metric of the successful development and implementation of a CSR policy. Consumers may wish to reward companies with good CSR records positively or even with non-negative information in the form of resilience to negative information about the
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The chemical abrasion mineral dissolution and isotope
2018-11-05
The chemical abrasion, mineral-dissolution and isotope dilution technique, also termed “conventional”, which requires a high degree of control on many parameters to ensure highest data quality (Schaltegger et al., 2015). A multi-step procedure described as follows were performed at the State Key Lab
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Previous work showed that lncRNAs show higher tissue
2018-11-05
Previous work showed that lncRNAs show higher tissue specificity compared to mRNAs (). The work of Ching et al. supported this notion, and extended it by showing a reduction of specificity after malignant transformation, which is consistent with the de-differentiation status of cancers widely observ
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One of the key findings of
2018-11-05
One of the key findings of this study is that the FcMBL ELLecSA detected PAMPs released from 47 of 55 (92%) clinically relevant pathogen species screened, including 14 of 16 of the most frequent bacterial species associated with sepsis at two major academic clinical medical centers (Brigham and Wome
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However one might question whether
2018-11-05
However, one might question whether effective compounds that do not bind to the C-terminal domain of PrP or that have other molecular targets besides PrP () will be excluded from this virtual screening. In the first case, docking with at least the 90–231 domain of the prion protein will prove useful
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Our findings of developmental changes
2018-11-05
Our findings of developmental changes in the injury responses of endogenous stem cells have particular therapeutic relevance for SCI. Recruitment of endogenous stem cells is a conceptually different approach to achieving the functional benefits previously observed with cell transplantation, which ca
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IDO small molecule inhibitors are currently being
2018-11-05
IDO1 small molecule inhibitors are currently being evaluated in clinical trials for a variety of cancers based on the supposition that they will help to enable an effective immune response directed against the tumor. This study indicates, however, that a more complex conceptualization of how the tum
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